Pal, Ashutosh published an article in 2021. The article was titled 《Synthesis of salicylate and salicylamide alcohols for the preparation of phosphorodiamidates and ifosfamide prodrugs》, and you may find the article in Oriental Journal of Chemistry.Application In Synthesis of 2-(Benzyloxy)acetaldehyde The information in the text is summarized as follows:
Different types of salicylate and salicylamide alcs. for the preparation of phosphorodiamidates and ifosfamide prodrugs were reported. In drug discovery and development, prodrugs were well-known for pharmacokinetic effects of pharmacol. nimble products. Almost 10% of drugs permitted, whole world were classified as prodrugs, where the application of a prodrug method during initial stages of development was an emergent fashion. In the experiment, the researchers used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Application In Synthesis of 2-(Benzyloxy)acetaldehyde)
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Application In Synthesis of 2-(Benzyloxy)acetaldehyde
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem