《Novel commercial scale synthetic approach for 5-cyanoindole: a potential intermediate for vilazodone hydrochloride, an antidepressant drug》 was published in Asian Journal of Chemistry in 2020. These research results belong to Venkatanarayana, M.; Nuchu, Ravi; Babu, H. Sharath; Garrepalli, Ganga Sravanthi; Tangallapall, Sudhakar. Synthetic Route of C5H13NO2 The article mentions the following:
Present work described the synthesis of title compound I, a common intermediate used in various synthetic route of the antidepressant vilazodone hydrochloride. The protocol was both robust and com. viable, utilizing readily available and low-cost materials and the isomers are environmental friendly than previously reported routes through its evading use of cyanide reagents and heavy metals. In the experiment, the researchers used many compounds, for example, N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Synthetic Route of C5H13NO2)
N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Synthetic Route of C5H13NO2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem