Synthetic Route of C7H7IOIn 2019 ,《Synthetic utilization of tetrafluoroethylene-containing silyl reagent (CH2=CHCF2CF2SiEt3) in Cu(I)-mediated cross-coupling reaction with various iodoarenes》 was published in Journal of Fluorine Chemistry. The article was written by Yakushijin, Ryosuke; Yamada, Shigeyuki; Konno, Tsutomu. The article contains the following contents:
The synthetic utilization of thermally stable as well as easy-handling tri-Et (1,1,2,2-tetrafluorobut-3-en-1-yl)silane as the tetrafluoroethylenating agent through Cu(I)-mediated cross-coupling reaction with various iodoarenes, which offered a promising building block for versatile CF2CF2-containing organic mols. through easy carbon chain elongation at both ends were revealed. Specifically, the above tetrafluoroethylene-containing silyl reagent, readily prepared from com. available 4-bromo-3,3,4,4-tetrafluorobut-1-ene, smoothly reacted with various iodoarenes in the presence of Cu(I), Ag(I) and pyridine in DMF at 60° for 16 h, the corresponding CF2CF2-containing aromatic compounds being afforded in moderate to good yields. Addnl., it was revealed that the coupling reaction dramatically facilitated when iodoarenes with an ortho-directing group, e.g., COOMe, were used as an electrophile, in which the acceleration effect was theor. proved to stabilize the whole reaction system by coordination of the carbonyl oxygen to the copper atom. After reading the article, we found that the author used 1-Iodo-2-methoxybenzene(cas: 529-28-2Synthetic Route of C7H7IO)
1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Synthetic Route of C7H7IO
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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem