《Titania-silica nanoparticles ensemblies assisted heterogeneous catalytic strategy for the synthesis of pharmacologically significant 2,3-diaryl-3,4-dihydroimidazo[4,5-b]indole scaffolds》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Geedkar, Deepika; Kumar, Ashok; Reen, Gagandeep Kour; Sharma, Pratibha. Recommanded Product: 673-22-3 The article mentions the following:
Present paper elicits the multicomponent reaction (MCR) strategy assisted by titania nanoparticles hosted on silica (TiO2.SiO2 NPs) as heterogeneous catalyst to synthesize a series of pharmacol. significant 2,3-diaryl-3,4-dihydroimidazo[4,5-b]indole derivatives The decrease in reaction time, low catalyst loading, high product yield (up to 92%), and excellent reusability of the catalyst (up to 7 cycles) put this protocol under the umbrella of green chem. tenets. Characterization of catalysts was achieved through a number of techniques viz., energy-dispersive X-ray (EDX) spectroscopy, field emission SEM (FESEM), powder X-ray diffraction (XRD), fourier transform IR (FTIR) spectra of adsorbed pyridine, temperature-programmed desorption of ammonia, and porosity measurements by nitrogen adsorption (Brunauer-Emmett-Teller [BET] method). Also, the structures of synthesized compounds were corroborated on the basis of FTIR, NMR (NMR), mass, and elemental analyses data. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 673-22-3)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Recommanded Product: 673-22-3
Referemce:
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Ether | (C2H5)2O – PubChem