《Reductive Hydroxymethylation of 4-Heteroarylpyridines》 was written by Hepburn, Hamish B.; Donohoe, Timothy J.. Recommanded Product: 10365-98-7 And the article was included in Chemistry – A European Journal in 2020. The article conveys some information:
The activation of pyridinium salts with electron-withdrawing heterocycles enabled an iridium-catalyzed reductive hydroxymethylation reaction to proceed smoothly, facilitating the preparation of useful 3D heteroaryl-substituted functionalized piperidines. The methodol. was used to prepare 3-hydroxymethylated analogs of pharmaceutical agents. Mechanistically, formaldehyde acts as both a hydride donor and the electrophile, leading to the formation of two new carbon-hydrogen bonds and one new carbon-carbon bond under relatively mild conditions. In the experimental materials used by the author, we found 3-Methoxyphenylboronic acid(cas: 10365-98-7Recommanded Product: 10365-98-7)
3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Recommanded Product: 10365-98-7
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem