Synthetic Route of C24H22N2O4On November 30, 2016 ,《Synthesis of new tetrazolyl derivatives of L- and D-phenylalanine》 appeared in Russian Journal of Organic Chemistry. The author of the article were Tolstyakov, V. V.; Tolstobrova, E. S.; Zarubina, O. S.; Popova, E. A.; Protas, A. V.; Chuprun, S. S.; Trifonov, R. E.. The article conveys some information:
(2S)- and (2R)-3-[4-(1H-Tetrazol-1-yl)phenyl]-2-aminopropionic acids were synthesized starting from L- and D-phenylalanine via azidation of Pr esters of (2S)- and (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-aminophenyl)propionic acids. The experimental process involved the reaction of Fmoc-D-Phe(4-NH2)-OH(cas: 324017-21-2Synthetic Route of C24H22N2O4)
Fmoc-D-Phe(4-NH2)-OH(cas: 324017-21-2) belongs to ethers.Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Synthetic Route of C24H22N2O4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem