《Synthesis and Functionalization of Allenes by Direct Pd-Catalyzed Organolithium Cross-Coupling》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Mateos-Gil, Jaime; Mondal, Anirban; Castineira Reis, Marta; Feringa, Ben L.. Computed Properties of C7H7BrO The article mentions the following:
A palladium-catalyzed cross-coupling between in situ generated allenyl/propargyl-lithium species and aryl bromides to yield highly functionalized allenes is reported. The direct and selective formation of allenic products preventing the corresponding isomeric propargylic product is accomplished by the choice of SPhos or XPhos based Pd catalysts. The methodol. avoids the prior transmetalation to other transition metals or reverse approaches that required prefunctionalization of substrates with leaving groups, resulting in a fast and efficient approach for the synthesis of tri- and tetrasubstituted allenes. Exptl. and theor. studies on the mechanism show catalyst control of selectivity in this allene formation. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0Computed Properties of C7H7BrO)
1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Computed Properties of C7H7BrO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem