《Quadruple Bond Forming Multicomponent Approach to 5-(3-chromenyl)-5H-chromeno[2,3-b]pyridines and Its Interaction with the Neuropeptide Y1 Receptor》 was published in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2020. These research results belong to Ryzhkov, Fedor V.; Ryzhkova, Yuliya E.; Elinson, Michail N.; Vereshchagin, Anatoly N.; Korolev, Victor A.; Egorov, Mikhail P.. Application of 673-22-3 The article mentions the following:
A new multicomponent, one-pot reaction yielding previously unknown 5-(4-hydroxy-2-oxo-2H-chromen-3-yl)-5H-chromeno[2,3-b]pyridines I (R1 = H, OMe, OEt, Br; R2 = H, OH, OMe; R3 = H, Br, Cl, NO2) in 52-94% yield has been found. This multicomponent approach allows to construct four new bonds to synthesize some 5H-chromeno[2,3-b]-pyridines I under mild conditions. Mol. docking and dynamics studies of the synthesized structures I were carried out to identify their interaction with the binding pocket of the neuropeptide Y1 receptor. After reading the article, we found that the author used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Application of 673-22-3)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Application of 673-22-3
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Ether | (C2H5)2O – PubChem