Koch, Vanessa; Brase, Stefan published the artcile< An Intramolecular Iodine-Catalyzed C(sp3)-H Oxidation as a Versatile Tool for the Synthesis of Tetrahydrofurans>, Product Details of C11H16O2, the main research area is THF preparation regioselective; alc carbon hydrogen activation oxidation cyclization iodine catalyst.
The formation of ubiquitous occurring THF patterns has been extensively investigated in the 1960s as it was one of the first examples of a non-directed remote C-H activation. These approaches suffer from the use of toxic transition metals in overstoichiometric amounts An attractive metal-free solution for transforming carbon-hydrogen bonds into carbon-oxygen bonds lies in applying economically and ecol. favorable iodine reagents. The presented method involves an intertwined catalytic cycle of a radical chain reaction and an iodine(I/III) redox couple by selectively activating a remote C(sp3)-H bond under visible-light irradiation The reaction proceeds under mild reaction conditions, is operationally simple and tolerates many functional groups giving fast and easy access to different substituted tetrahydrofurans.
European Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Product Details of C11H16O2.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem