Phan Thi Thanh, Nga; Dang Thi Thu, Huong; Tone, Masaya; Inoue, Hayato; Iwasa, Seiji published the artcile< Synthesis of Oxindole Derivatives via Intramolecular C-H Insertion of Diazoamides Using Ru(II)-Pheox Catalyst>, Electric Literature of 10541-78-3, the main research area is oxindole preparation regioselective; diazoacetamide preparation insertion reaction ruthenium catalyst.
This work presented the efficient intramol. aromatic C-H insertion of diazoacetamide. The diazo compounds (except for 1k) were converted into their corresponding oxindoles via an intramol. C-H insertion reaction in the presence of a Ru catalyst. The Ru-Pheox catalyst was shown to be highly efficient in this transformation in terms of the regioselectivity, producing the desired products in excellent yield (99%). The efficiency of the Ru catalyst reached 580 (TON) and 156 min-1 (TOF).
Tetrahedron published new progress about Acetamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (diazo). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Electric Literature of 10541-78-3.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem