Leonard, Nicholas M.;Oswald, Matthew C.;Freiberg, Derek A.;Nattier, Bryce A.;Smith, Russell C.;Mohan, Ram S. published 《A Simple and Versatile Method for the Synthesis of Acetals from Aldehydes and Ketones Using Bismuth Triflate》 in 2002. The article was appeared in 《Journal of Organic Chemistry》. They have made some progress in their research.Product Details of 2235-01-0 The article mentions the following:
Acetals are obtained in good yields by treatment of aldehydes and ketones with trialkyl orthoformates and the corresponding alc. in the presence of 0.1 mol % Bi(OTf)3·4H2O. A simple procedure for the formation of acetals of diaryl ketones has also been developed. The conversion of carbonyl compounds to the corresponding 1,3-dioxolanes using ethylene glycol is also catalyzed by Bi(OTf)3·4H2O (1 mol %). Two methods, both of which avoid the use of benzene, have been developed. The experimental procedure involved many compounds, such as Dimethoxydiphenylmethane (cas: 2235-01-0) .
Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Product Details of 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem