The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.SDS of cas: 2235-01-0
SDS of cas: 2235-01-0In 2008, Crich, David;Li, Ming published 《Block Synthesis of Tetra- and Hexasaccharides (β-D-Glycero-D-manno-Hepp-(1→4)-[α-L-Rhap-(1→3)-β-D-glycero-D-manno-Hepp-(1→4)]n-α-L-Rhap-OMe (n = 1 and 2)) Corresponding to Multiple Repeat Units of the Glycan from the Surface-Layer Glycoprotein from Bacillus thermoaerophilus》. 《Journal of Organic Chemistry》published the findings. The article contains the following contents:
A fully stereocontrolled block synthesis of the title tetra- and hexasaccharides has been achieved taking advantage of the ability of the 4,6-O-benzylidene acetal to control the stereochem. of the β-D-glycero-D-mannoheptopyranoside unit and of a 2,3-O-diphenylmethylene acetal to install the α-L-rhamnopyranosidic linkages. Comparison of the spectral data for the hexasaccharide with that of the natural isolate confirms the structure of this very unusual and structurally challenging glycan. The experimental procedure involved many compounds, such as Dimethoxydiphenylmethane (cas: 2235-01-0) .
The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.SDS of cas: 2235-01-0
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem