Category: ethers-buliding-blocksIn 2010, Jung, Misuk;Yoon, Jieun;Kim, Hak Sung;Ryu, Jae-Sang published 《Mild and chemoselective synthesis and deprotection of geminal diacetates catalyzed by titanium(IV) halides》. 《Synthesis》published the findings. The article contains the following contents:
A novel, mild, and chemoselective method was developed for the preparation of gem-diacetates from aldehydes and Ac2O in the presence of TiF4 (1-5 mol%) under solvent-free conditions at room temperature The reaction showed a high chemoselectivity toward aldehydes in the presence of ketones. Moreover, TiF4 also catalyzed the deprotection of gem-diacetates to the corresponding aldehydes in water. .This efficient and simple method has several benefits, including the use of an inexpensive catalyst, solvent-free conditions, mild reaction temperatures, and high yields, which make it both cost-effective and environmentally friendly. And Dimethoxydiphenylmethane (cas: 2235-01-0) was used in the research process.
Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Category: ethers-buliding-blocks The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem