The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 4-(Piperazin-1-yl)phenol( cas:56621-48-8 ) is researched.Synthetic Route of C10H14N2O.Ryu, Seong-Ryuall published the article 《Synthesis of cycloalkylcarbamoyl substituted ketoconazole derivatives as antifungal agents》 about this compound( cas:56621-48-8 ) in Kongop Hwahak. Keywords: cycloalkylcarbamoyl ketoconazole derivative fungicide preparation; antifungal cycloalkylcarbamoyl ketoconazole derivative preparation. Let’s learn more about this compound (cas:56621-48-8).
In an effort to prepare new antifungal agents, two new title derivatives I (R = cyclopropyl, cyclohexyl) were synthesized by the reaction of substituted piperazine II with N-cycloalkylcarbamoyl derivatives ClCH2CONHR.
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Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem