Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 73590-85-9, is researched, SMILESS is CC1=CN=C(CSC2=NC3=CC(OC)=CC=C3N2)C(C)=C1OC, Molecular C17H19N3O2SJournal, Article, Journal of Solution Chemistry called Solubility of Omeprazole Sulfide in Different Solvents at the Range of 280.35-319.65 K, Author is Li, Yihua; Yang, Wenge; Zhang, Tuan; Wang, Chaoyuan; Wang, Kai; Hu, Yonghong, the main research direction is solubility omeprazole sulfide solvent temperature range; Gravimetric method; Omeprazole sulfide; Purification; Solubility; Solution thermodynamics.Safety of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole.
Solubility data were measured for omeprazole sulfide in ethanol, 95 mass-% ethanol, Et acetate, isopropanol, methanol, acetone, n-butanol and n-propanol in the temperature range from 280.35 to 319.65 K by employing the gravimetric method. The solubilities increase with temperature and they are in good agreement with the calculated solubility of the modified Apelblat equation and the λh equation. The exptl. solubility and correlation equation in this work can be used as essential data and model in the purification process of omeprazole sulfide. The thermodn. properties of the solution process, including the Gibbs energy, enthalpy, and entropy were calculated using the van’t Hoff equation.
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Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem