The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(SMILESS: CC1=CN=C(CSC2=NC3=CC(OC)=CC=C3N2)C(C)=C1OC,cas:73590-85-9) is researched.Product Details of 2150-55-2. The article 《Determination of omeprazole and metabolites in plasma and urine by liquid chromatography》 in relation to this compound, is published in Journal of Chromatography, Biomedical Applications. Let’s take a look at the latest research on this compound (cas:73590-85-9).
Omeprazole (I) [73590-58-6], a substituted benzimidazole and a new gastric acid inhibitor, was determined in plasma and urine, together with 3 of its metabolites: the sulfide [73590-85-9], the sulfone [88546-55-8] and the hydroxy compound [92340-57-3]. The methods comprised extraction from the biol. materials with CH2Cl2, followed either by direct injection of the extract onto a normal-phase liquid chromatog. column or evaporation, dissolution, and injection onto a reversed-phase system. The compounds were detected by UV spectrometry. The absolute recoveries obtained were mostly >95%. The min. determinable concentration of omeprazole was 20 nmol/L plasma (relative standard deviation 10-15%) and 50 nmol/L in urine. The metabolites could also be determined at the same levels.
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Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem