Recommanded Product: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole, is researched, Molecular C17H19N3O2S, CAS is 73590-85-9, about Solubility of Omeprazole Sulfide in Different Solvents at the Range of 280.35-319.65 K. Author is Li, Yihua; Yang, Wenge; Zhang, Tuan; Wang, Chaoyuan; Wang, Kai; Hu, Yonghong.
Solubility data were measured for omeprazole sulfide in ethanol, 95 mass-% ethanol, Et acetate, isopropanol, methanol, acetone, n-butanol and n-propanol in the temperature range from 280.35 to 319.65 K by employing the gravimetric method. The solubilities increase with temperature and they are in good agreement with the calculated solubility of the modified Apelblat equation and the λh equation. The exptl. solubility and correlation equation in this work can be used as essential data and model in the purification process of omeprazole sulfide. The thermodn. properties of the solution process, including the Gibbs energy, enthalpy, and entropy were calculated using the van’t Hoff equation.
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