Discovery of 19056-40-7

According to the analysis of related databases, 19056-40-7, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 19056-40-7, name is 4-Bromo-3-methoxyaniline, This compound has unique chemical properties. The synthetic route is as follows., name: 4-Bromo-3-methoxyaniline

2-(2-chlorophenylaminoacetic acid (lSOmg. 808 imoD and 4-bromo-3-methoxyaniline (171 mg, 849 imol) were combined with dichloromethane (10 m). At 0¡ãC N-(3-dimethylaminopropyl)-N?-ethylcarbodiimide hydrochloride (163 mg, 849 imol) was added. The reaction mixture was stirred at O ¡ãC for 30 mm, then at RT oyernight. The mixture was poured on water (20 ml) and extracted with dichloromethane (3 x 15 ml). chromatography (silicagel, ethyl acetate / heptane = 20:80 to 50:50) yielded N-(4-bromo-3-methoxyphenyl)-2-(2- chlorophenylamino)acetamide (225 mg, 75percent) as yellow solid. MS: mle =371.1 [M+H].

According to the analysis of related databases, 19056-40-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; CECCARELLI, Simona M.; JAGASIA, Ravi; JAKOB-ROETNE, Roland; PETERS, Jens-Uwe; WICHMANN, Juergen; WO2014/79850; (2014); A1;,
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