Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 20781-20-8, name is (2,4-Dimethoxyphenyl)methanamine, A new synthetic method of this compound is introduced below., Formula: C9H13NO2
Weighing 167 mg of 2,4-dimethoxybenzylamine, 6.1 mg of Ru catalyst,3.0 mL of ethanol was weighed, 290 mg of 5-HMF was weighed,In 10mL autoclave mixed evenly, the system with 10bar hydrogen replacement 3 times,The reaction initial hydrogen pressure was 20 bar, the temperature was 110 C,The reaction time was 12 h. After the end of the reaction, the ethanol was removed under reduced pressure,The residue was separated using a silica gel columnWith a color solid of 325.4 mg, yield 84%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Dalian Institute of Chemical Physics; Zhang Zongchao; Xu Zhanwei; Wan Lu; Yan Peifang; (17 pag.)CN106632165; (2017); A;,
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