Adding a certain compound to certain chemical reactions, such as: 74137-36-3, name is 1,3-Dibromo-5-methoxybenzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 74137-36-3, Application In Synthesis of 1,3-Dibromo-5-methoxybenzene
2 mmol 3,5-dibromoanisole were dissolved in 10 ml THF and cooled to -78C. 2.4 mmol of n- BuLi were added dropwise and stirring was continued for 15 min. 3 mmol of methyl iodide were added and the mixture was allowed to slowly warm to ca. -200C over a period of ca. 2 h. IM HCl and dichloromethane were added and the phases were separated. 1.65 mmol of crude 3-bromo-5- methylanisole were taken to the next step without further purification.
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Reference:
Patent; KARO BIO AB; WO2008/43567; (2008); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem