Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2944-49-2, name is 1-Methoxy-2,3-dimethylbenzene, A new synthetic method of this compound is introduced below., Recommanded Product: 2944-49-2
Carbon tetrachloride (100 ml) will be 3 – methoxy ortho-xylene crude product dilution dissolved, added to the mixed liquid in the N – bromo succinimide (NBS, 34.0 g, 190.4 mmol) and 2,2′-azobisisobutyronitrile (AIBN, 0.30 g), after mixing the heated to 77 C stirring reflux 24 h. TLC detection reaction has been substantially completely, cooling stop stirring, filtering the reaction solution, saturated sodium bisulfite solution for fragrance (50 ml × 2) washing twice, static layering, the collection of organic phase, the organic phase dried with anhydrous sodium sulfate 12 h. Filtering, environment friendly with silica gel column chromatography, eluting agent is pure petroleum ether, to obtain white solid 7.70 g, yield 69.2%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Shandong University; Ma Shutao; Jin Chaobin; Wang Yinhu; Gu Xinjie; (32 pag.)CN108929260; (2018); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem