Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 18800-30-1, name is 1-Bromo-4-(2-bromoethoxy)benzene, A new synthetic method of this compound is introduced below., COA of Formula: C8H8Br2O
In a 100 ml two-necked flask, 40 ml of DMF was added,4- (2-bromoethoxy) -bromobenzene (9.48 g, 47 mmol)Potassium phthalimide (10.47 g, 56 mmol) was reacted at 90 C for 2 h.After the reaction, DMF was removed by steaming and then extracted three times with chloroform to combine the organic phase,Add the appropriate amount of anhydrous MgSO4, standing for half an hour. The MgSO4 was removed by filtration,The chloroform was removed by rotary distillation and purified by column chromatography (dichloromethane as eluent) to give a white solid,Yield 85%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Nanjing Tech University; Gao Deqing; Pan Zhenhuan; Tong Tong; Li Bobo; Liu Minglun; Huang Wei; (9 pag.)CN106518691; (2017); A;,
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