Adding a certain compound to certain chemical reactions, such as: 4463-59-6, name is 1-(2-Bromoethoxy)-2-methoxybenzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 4463-59-6, Safety of 1-(2-Bromoethoxy)-2-methoxybenzene
EXAMPLE 68 1-[2-(2-Methoxyphenoxy)ethyl]-4-benzamidopiperidine 2-(2-Methoxyphenoxy)ethyl bromide (2.31 g.), 4-benzamidopiperidine (2.04 g.) and anhydrous potassium carbonate (1.38 g.) were well mixed and heatedon a steam bath for 4 hr. The resulting mass was crushed and stirred in water (200 ml.) at 60 for 12 hr. Filtration afforded the crude base of the title compound (2.95 g.). Conversion to the hydrochloride by solution in ethanol/HCl and precipitation with ether provided 3.01 g. of the title compound, as the hydrochloride m.p. 193.4. Analysis: Found C, 64.74; H, 7.08; N, 7.14. C21 H26 N2 O3. HCl requires C, 64.52; H, 6.96; N, 7.17%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(2-Bromoethoxy)-2-methoxybenzene, and friends who are interested can also refer to it.
Reference:
Patent; John Wyeth & Brother Limited; US3992389; (1976); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem