Application of 109-85-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 109-85-3, name is 2-Methoxyethylamine belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Compound4-amino-N-hydroxy-1,2,5-oxadiazole-3-carbamimidinyl chloride(4.0g, 24.7mmol)Soluble in ethyl acetate (40 ml),2-methoxyethane-1-amine (2.29 ml, 25.9 mmol) was added to the ice bath for 5 minutes.Additional triethylamine (5.16 ml, 37.05 mmol) was added and stirred for two hours until the reaction was complete.Washed with water, washed with saturated brine, dried over anhydrous sodium sulfate,Concentration under reduced pressure in vacuo gave compound 4-amino-N’-hydroxy-N-(2-methoxyethyl)-1,2,5-oxadiazol-3-carboximidamide 1d (4.5 g, 92 %).
The synthetic route of 2-Methoxyethylamine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jiangsu Hansoh Pharmaceutical Group Co., LTD (CN); Shanghai Hansoh Biomedical Co.,Ltd (CN); WU, SHENG HUA; GUO, FENG YING; LI, KAI LONG; HUANG, ZHI QIANG; BAO, RUDI; (94 pag.)TW2018/23219; (2018); A;,
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