Synthetic Route of 41406-00-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 41406-00-2, name is 3-Isopropoxyaniline belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Reference Example 13-1; To Compound 1 (1.00 g) were added Compound 2 (3.00 ml) and trifluoroacetic acid (0.05 ml), and the mixture was heated to reflux for 24 hours. The reaction mixture was cooled, and then concentrated under reduced pressure. To a solution of the residue in ethanol (20 ml) was added sodium borohydride (1.00 g) under ice-cooling, and the mixture was stirred for an hour, and then heated to reflux for 2 hours. The reaction mixture was cooled, and then thereto was added water. The solvent was concentrated to about halves under reduced pressure, and extracted with ethyl acetate. The extracted layer was washed with saturated saline, and dried over anhydrous magnesium sulfate, and then the solvent was distilled away under reduced pressure. The residue was purified by silica gel column chromatography (eluent n-hexane-ethyl acetate 100:0 to 50:50 gradient) to give Compound 3 (0.96 g) as a pale yellow oily substance.MS (APCI) 166 [M+H]+
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Isopropoxyaniline, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Yamaguchi, Tetsuo; Ushirogochi, Hideki; Hirai, Miki; Imanishi, Yasuhiro; US2012/16117; (2012); A1;,
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