Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 886762-08-9, name is 5-Bromo-2-(trifluoromethoxy)aniline, This compound has unique chemical properties. The synthetic route is as follows., Formula: C7H5BrF3NO
General procedure: Compound (6) (0.38 g, 0.7 mmol), 1-[[(3,5-dimethyl phenyl)amino]carbonyl] (0.34 g, 0.92 mmol) was dissolved in anhydrousCH2Cl2 (10 mL), and HATU (0.63 g,1.66 mmol) was added, themixture was stirred on the ice-bath for 30 min, then 0.13 mLanhydrous triethylamine in anhydrous CH2Cl2 was slowly addeddropwise to the above mixture, after that, the ice bath wasremoved, and the mixturewas reacted at room temperature for 8 h.The product was extracted with CH2Cl2 (30 mL 3), washed withwater and brine (100 mL 3), and dried over Na2SO4. After filtrationand concentration in vacuo, the residues was purified by silicagel flash chromatogrphy gave (10k) (0.12 g, 25%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 886762-08-9.
Reference:
Article; Zhang, Lin; Shan, Yuanyuan; Li, Chuansheng; Sun, Ying; Su, Ping; Wang, Jinfeng; Li, Lisha; Pan, Xiaoyan; Zhang, Jie; European Journal of Medicinal Chemistry; vol. 127; (2017); p. 275 – 285;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem