In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 6298-96-0 as follows. Computed Properties of C9H13NO
(a). ( 1 S)-JV- r 1 -(4-Methoxy-phenyl>ethyll -3 -oxo-butyramide; To a solution of (S)-l-(4-methoxy-phenyl)-ethylamine (25 g) in dichloromethane (60 mL) was added TEA (20 g) and DMPA (200 mg). Then a solution of 4-methylene- oxetan-2-one (16.7 g) in dichloromethane (60 ml) was added over a period of 30 minutes and then stirred at 20 0C for 18 h. The mixture was washed with IM HCl, aq. NaHCO3 and aq. NaCl. The organic layer was dried (MgSO4), filtered and concentrated in vacuo. EPO
According to the analysis of related databases, 6298-96-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; N.V. ORGANON; WO2006/117368; (2006); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem