36865-41-5, name is 1-Bromo-3-methoxypropane, belongs to ethers-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 36865-41-5
To a solution of the compound of Reference Example 50 (114.3 mg, 0.182 mmol) in DMF (2 mL), potassium carbonate (50.3 mg, 0.364 mmol) and 1-bromo-3-methoxypropane (41.8 mg, 0.273 mmol) were added, and the mixture was stirred at 50C for 1 hour. A saturated aqueous solution of ammonium chloride was added to the reaction mixture, followed by extraction with ethyl acetate. The organic layer was washed with a saturated aqueous solution of ammonium chloride twice and with a saturated saline solution once, then dried over sodium sulfate and filtered, and the filtrate was concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography to obtain the title compound (121.2 mg, 95%). MS (ESI+) 700 (M+1, 68%)
The synthetic route of 36865-41-5 has been constantly updated, and we look forward to future research findings.