Application of 2,2-Dimethoxyethanamine

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 22483-09-6.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 22483-09-6, name is 2,2-Dimethoxyethanamine, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 2,2-Dimethoxyethanamine

A solution of 2-thiophenecarboxaldehyde (Ig, 8.93mmol) and aminoacetaldehyde dimethylacetal (1.4g, 13.4mmol) in DCM (23OmL) was stirred at 350C for 1 h.Sodium triacetoxyborohydride (5.68g, 27mmol) was added and the reaction stirred at r.t. for 5 hours. NaHCO3 (saturated solution, 10OmL) was added and the organics were collected, washed (brine), dried (MgSO4) and concentrated in vacuo. The residue was purified via flash chromatography eluting with 50% EtOAc/isohexane to afford the title compound as a yellow oil. Yield 1.6g (90%): HPLC retention time, 2.76min (Solvent: CH3CN/H2O/0.05% NH3, 5-95% gradient H2O-6min. Column: EPO Xterra 50 x 4.60 i.d., Cl 8 reverse phase. Flow rate: 1.5mL/min.). Mass spectrum (ES+) m/z 202 (M + H).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 22483-09-6.