Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 102-52-3, name is 1,1,3,3-Tetramethoxypropane, A new synthetic method of this compound is introduced below., Computed Properties of C7H16O4
In a 1 L reaction flask, 100 g of tetramethoxypropane was charged successively,58.8 g of N-methylaniline, stirred for 10 minutes,Control the internal temperature below 30 , drop 22g 20% hydrochloric acid,Dripping at about 24 C for 2.5 hours, adding 200 g of toluene,Control in 30 below the drop of 20% of the liquid caustic so that the water layer pH 6 ~ 7,The layers were separated and the aqueous layer was extracted with toluene and the organic layers were combined.Washed with saturated brine three times, and then separated to separate the water layer, the organic layer first vacuum recovery solvent,And then collecting 60 to 70 C / 40 mmHg fraction,To give 3- (N-methyl-N-phenyl) aminopropenal83.1g content of 99.6%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Jiangsu Jingye Pharmaceutical Co., Ltd.; Chu, Zhewei; Yue, Bo; Ye, Yin; (4 pag.)CN106431942; (2017); A;,
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