The dehydrative etherification of benzyl alcohols via mechanochemical reaction was written by Bian, Meng-Hua;Lu, Li-Yu;Zhang, Pu;Guo, Zhi-Xin. And the article was included in Tetrahedron Letters in 2022.Quality Control of (4-Methoxyphenyl)methanol This article mentions the following:
A facile, solvent-free, lower-cost, and efficient high-speed ball milling reaction catalyzed by Cu(NO3)2璺?H2O/P2O5 were developed for the synthesis of sym. ethers ArCH(R)OCH(R)Ar (R = H, Me, Et, Ph; Ar = 4-chlorophenyl, naphthalen-1-yl, thiophen-2-yl, etc.) and 1-(1,2,3,4-tetrahydronaphthalen-1-yloxy)-1,2,3,4-tetrahydronaphthalene from dehydration of benzyl alcs. ArCH(R)OH and 1,2,3,4-tetrahydronaphthalen-1-ol by taking a benzylic carbocation as intermediate. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Quality Control of (4-Methoxyphenyl)methanol).
(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O閳ユ椊 or N閳ユ椊 bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Quality Control of (4-Methoxyphenyl)methanol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem