Use of high-frequency conductometry in organic chemistry. IV. Acid-base properties of aromatic alcohols of the phenylpropane and guaiacylpropane series was written by Cemeris, M.;Galochkin, A. I.. And the article was included in Koksnes Kimija in 1974.Reference of 3929-47-3 This article mentions the following:
The acidities of phenylalkanols decreased in the order p-O2NC6H4CH2OH > PhCH2OH > PhCH:CHCH2OH > PhCH2CH2OH > PhCHEtOH > Ph(CH2)3OH; those of veratryl alcs. decreased in the order ZCH:CHCH2OH [Z = 3,4-(MeO)2C6H3] > Z(CH2)3OH > ZCHEtOH; those of guaiacylpropanols were comparable with that of PhCH2OH. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Reference of 3929-47-3).
3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers feature bent C閳ユ彊閳ユ弲 linkages. In dimethyl ether, the bond angle is 111鎺?and C閳ユ彊 distances are 141 pm. The barrier to rotation about the C閳ユ彊 bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Reference of 3929-47-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem