Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1758-46-9, name is 2-Phenoxyethylamine, A new synthetic method of this compound is introduced below., COA of Formula: C8H11NO
EXAMPLE 1 : Preparation of 2-phenoxyethylamine 2-hydroxypropane-1 ,2,3- tricarboxylate (= 2-phenoxyethylamine citrate): compound IV2-Phenoxyethylamine 2-hydroxypropane-1 ,2,3-tricarboxylate (compound IV)is obtained by salification of phenoxyethylamine with citric acid, according to the following reaction: Ethanol Citric acid 15 h room temperature phenoxyethylamineMW = 137 18 MW = 137 18 192 13 C8H11 NO C6H8O7120 g of phenoxyethylamine (RN 1758-46-9 commercially available from the company Aldrich, ref. 40,726-7) are dissolved in 2L of ethanol in a reactor equipped with a mechanical stirrer. 56.04 g of citric acid are then added. A compact precipitate rapidly forms (vigorous stirring required).After stirring for 15 hours, the compact solid is filtered off on a sinter funnel and is then washed with 150 ml of ethanol. The solid obtained is dried in a desiccator under vacuum at 500C. Recovered mass: 145 g. The reaction yield is 82percent.Phenoxyethylamine (starting material) may also be prepared according to one of the processes described in the literature and indicated previously in the description (cf. hereinabove).
The synthetic route of 1758-46-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; L’OREAL; DALKO, Maria; LEREBOUR, Geraldine; WO2010/4016; (2010); A1;,
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