The origin of a common compound about 20469-65-2

According to the analysis of related databases, 20469-65-2, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20469-65-2, name is 1-Bromo-3,5-dimethoxybenzene, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 1-Bromo-3,5-dimethoxybenzene

Condensation reaction: in with a thermometer, condenser 250 ml bottle to join four 21.9g 5 – bromo – m dimethyl ether {melting point 62 – 66 C; appearance: white solid; nuclear magnetic:1H NMR (CDCl3, 400MHz) delta (ppm) data are as follows: 3.82 (s, 6H, CH3), 6.37 (t, 1H, Ar – H), 6.81 (d, 2H, Ar – H)}, 12.8g bromopropylene, 20.4g triethylamine, 2.2g dppp nickel chloride, 130 ml methyl tert-butyl ether, magnetic stirring, oil bath heating, when the temperature rises to 50 C and maintaining at 4 hours, after the reaction is cooled to ambient temperature, for 60 ml 10% hydrochloric acid aqueous solution washing the reaction liquid, water washed to neutral, the organic layer is distilled under reduced pressure to obtain 17.4g 5 – propenyl – m dimethyl ether {melting point 97 – 100 C; appearance: white solid; nuclear magnetic resonance:1

According to the analysis of related databases, 20469-65-2, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Weifang Xian Da Chemical Co., Ltd.; Li Kai; Wang Guangyue; Yang Qiwei; Zou Yabo; (7 pag.)CN106748673; (2017); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem