Cobalt(II) chloride hexahydrate-diisopropylamine catalyzed mild and chemoselective reduction of carboxylic esters with sodium borohydride was written by Jagdale, Arun R.;Paraskar, Abhimanyu S.;Sudalai, Arumugam. And the article was included in Synthesis in 2009.Product Details of 3929-47-3 This article mentions the following:
The Co-catalyzed reduction of unsaturated α-cyano carboxylates using NaBH4 leads to the corresponding saturated cyano alcs. in high yields. In particular, the new catalytic system CoCl2-(Me2CH)2NH in combination with NaBH4 showed excellent activity in the chemoselective reduction of a variety of carboxylates to the corresponding alcs. in good to excellent yields under mild conditions. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Product Details of 3929-47-3).
3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Product Details of 3929-47-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem