Germain, Andrew R. et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2013 | CAS: 6972-61-8

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C11H12O4

Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells was written by Germain, Andrew R.;Carmody, Leigh C.;Nag, Partha P.;Morgan, Barbara;VerPlank, Lynn;Fernandez, Cristina;Donckele, Etienne;Feng, Yuxiong;Perez, Jose R.;Dandapani, Sivaraman;Palmer, Michelle;Lander, Eric S.;Gupta, Piyush B.;Schreiber, Stuart L.;Munoz, Benito. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2013.Synthetic Route of C11H12O4 This article mentions the following:

A high-throughput screen (HTS) was conducted against stably propagated cancer stem cell (CSC)-enriched populations using a library of 300,718 compounds from the National Institutes of Health (NIH) Mol. Libraries Small Mol. Repository (MLSMR). A cinnamide analog displayed greater than 20-fold selective inhibition of the breast CSC-like cell line (HMLE_sh_Ecad) over the isogenic control cell line (HMLE_sh_eGFP). Herein, we report structure-activity relationships of this class of cinnamides for selective lethality towards CSC-enriched populations. In the experiment, the researchers used many compounds, for example, 3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8Synthetic Route of C11H12O4).

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C11H12O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem