Modeling of physico-chemical properties by topological indices was written by Katona, G.;Panea, Teodora. And the article was included in Acta Universitatis Cibiniensis, Seria F: Chemia in 2005.Recommanded Product: 1877-75-4 This article mentions the following:
A study of the quant. structure-property and structure-activity relationship QSPR/QSAR is presented for a set of aryloxyacetic acid derivatives Some QSAR properties were also calculated and correlated with topol. descriptors. As mol. descriptors the Cluj and Cluj type, Szeged and some classical indexes were used. Cluj and Szeged properties indexes considering the electronegativity, mass and 3D-geometry were also used. Some models for predicting LogP, hydration energy and Ka of the above set of acids are proposed. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Recommanded Product: 1877-75-4).
2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Recommanded Product: 1877-75-4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem