Sun, Pengli published the artcileSynthesis of Fmoc-N-methyl-L-phenylalanine with microwave-assisted, Safety of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, the publication is Guangzhou Huagong (2012), 40(10), 64-65, database is CAplus.
Fmoc-protected N-methyl-L-phenylalanine was synthesized under the presence of trifluoroacetic acid and anhydrous aluminum chloride as catalyzer and the triethylsilane as reduction, in which the Fmoc-protected L-phenylalanine was used as original material, passing though the generated intermediate 5-oxazolidinone with microwave assisted heating method. The result showed that using the microwave assisted heating method, the reaction time greatly reduced and the mean total yield increased to 82%, and the composite catalyzer of trifluoroacetic acid and anhydrous aluminum chloride could avoid generating the byproduct Fmoc-Tic-OH and save original material.
Guangzhou Huagong published new progress about 77128-73-5. 77128-73-5 belongs to ethers-buliding-blocks, auxiliary class Inhibitor, name is (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid, and the molecular formula is C2H8Cl2N4S2, Safety of (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem