Grolik, Jaroslaw’s team published research in Tetrahedron Letters in 99 | CAS: 91-16-7

Tetrahedron Letters published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Computed Properties of 91-16-7.

Grolik, Jaroslaw published the artcileRegioselective synthesis of the 4,5-dialkoxy-2-nitroanilines bearing two different alkoxy substituents, Computed Properties of 91-16-7, the publication is Tetrahedron Letters (2022), 153830, database is CAplus.

This article reported the regioselective and chemoselective synthesis of 4,5-dialkoxy-2-nitroanilines I [R1 = Me, Et, i-Bu, etc.; R2 = Me, i-Pr, n-Bu, etc.] substituted with two alkoxys at C-4 and C-5. Here the optimization protocol of the transetherification reaction used to synthesize 20 new compounds with good to excellent yields (50-92%) was showed. A simple and efficient one-step procedure was described that could be applied to obtain a significant number of pharmacol. active compounds, including antimalarial drug Primaquine analogs.

Tetrahedron Letters published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Computed Properties of 91-16-7.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem