Ramachandran, Rangasamy published the artcileRuthenium(II) complexes containing a phosphine-functionalized thiosemicarbazone ligand: synthesis, structures and catalytic C-N bond formation reactions via N-alkylation, Recommanded Product: N-(4-Methoxybenzyl)pyridin-2-amine, the publication is RSC Advances (2015), 5(15), 11405-11422, database is CAplus.
A series of ruthenium(II) complexes incorporating a thiosemicarbazone chelate tethered with a diphenylphosphine pendant have been studied. Thus, [(PNS-Et)RuCl(CO)(PPh3)] (1), [N,S-(PNS-Et)RuH(CO)(PPh3)2] (2) and [(PNS-Et)RuCl(PPh3)] (3) were synthesized by reactions of various RuII precursors with 2-(2-(diphenylphosphino)benzylidene)-N-ethylthiosemicarbazone (PNS-Et). However, complexation of PNS-Et with an equimolar amount of [RuCl2(DMSO)4] resulted in two different entities [(PNS-Et)RuCl(DMSO)2] (4) and [(PNS-Et)2Ru] (5) with different structural features in a single reaction. All the RuII complexes have been characterized by anal. and various spectroscopic techniques. Compounds 1–5 were recrystallized, and the x-ray crystal structures have been reported for 1, 2 and 5. In the complexes 1 and 3–5 the ligand coordinated in a tridentate monobasic fashion by forming PNS five- and six-membered rings, whereas in 2, the ligand coordinated in a bidentate monobasic fashion by forming a strained NS four-membered ring. Furthermore, compounds 1–5 showed catalytic activity in N-alkylation of heteroaromatic amines. Notably, complexes 1–3 are very efficient catalysts toward N-alkylation of a wide range of heterocyclic amines with alcs. In the presence of a catalytic amount of 2 with 50 mol% of KOH, N1,C5-dialkylation of 4-phenylthiazol-2-amine has been investigated. Reaction of in situ generated aldehyde with amine yields the N1,C5-dialkylated products through the hydride ion transformation from alc. Complexes 1–3 also catalyzed a variety of coupling reactions of benzyl alcs. and sulfonamides, which were realized often with 99% isolated yields. Advantageously, only one equivalent of the primary alc. was consumed in the process.
RSC Advances published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Recommanded Product: N-(4-Methoxybenzyl)pyridin-2-amine.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem