Gaucher-Wieczorek, Florence S.’s team published research in Journal of Combinatorial Chemistry in 12 | CAS: 845551-45-3

Journal of Combinatorial Chemistry published new progress about 845551-45-3. 845551-45-3 belongs to ethers-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (3-((2-Chlorobenzyl)oxy)phenyl)boronic acid, and the molecular formula is C13H12BClO3, Name: (3-((2-Chlorobenzyl)oxy)phenyl)boronic acid.

Gaucher-Wieczorek, Florence S. published the artcileFluorous Tagged N-Hydroxy Phthalimide for the Parallel Synthesis of O-Aryloxyamines, Name: (3-((2-Chlorobenzyl)oxy)phenyl)boronic acid, the publication is Journal of Combinatorial Chemistry (2010), 12(5), 655-658, database is CAplus and MEDLINE.

The parallel synthesis of O-aryloxyamines remains an unfulfilled need in the field of medicinal chem. and fragment-based approaches. To fill this gap a solution-phase two-step process based on (1) a copper-catalyzed cross-coupling of aryl boronic acids with a fluorous tagged N-hydroxyphthalimide, and (2) a supported aminolysis was designed and optimized using Taguchi’s method. A library of O-aryloxyamines was synthesized in high yields with high purity and diversity.

Journal of Combinatorial Chemistry published new progress about 845551-45-3. 845551-45-3 belongs to ethers-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (3-((2-Chlorobenzyl)oxy)phenyl)boronic acid, and the molecular formula is C13H12BClO3, Name: (3-((2-Chlorobenzyl)oxy)phenyl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem