Nicolaou, K. C. published the artcileTotal Synthesis and Biological Evaluation of Monorhizopodin and 16-epi-Monorhizopodin, Safety of (+)-B-Methoxydiisopinocampheylborane, the publication is Angewandte Chemie, International Edition (2011), 50(5), 1139-1144, S1139/1-S1139/94, database is CAplus and MEDLINE.
A highly convergent total synthesis of monorhizopodin (I) and 16-epi-monorhizopodin was developed, rendering the monomeric homologs of the powerful antitumor agent rhizopodin available for biol. investigations. Preliminary studies showed these compounds to be endowed with actin-binding properties but devoid of any associated cytotoxicity, thus posing interesting questions regarding the role of the dimeric nature of rhizopodin in its mode of action. Further studies directed toward the elucidation of the mechanism of action and the differences of rhizopodin and its monomeric homologs, monorhizopodin and 16-epi-monorhizopodin, as well as the total synthesis of the former are in progress.
Angewandte Chemie, International Edition published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Safety of (+)-B-Methoxydiisopinocampheylborane.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem