Topolovcan, Nikola published the artcileChemoselective and Regioselective Synthesis of Spiroisoindolinone Indenes via an Intercepted Meyer-Schuster Rearrangement/Intramolecular Friedel-Crafts Alkylation Relay, SDS of cas: 91-16-7, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.
A Bronsted acid-catalyzed reaction between isoindolinone-derived propargylic alcs. I [R = H, 2-Me, 3-Cl, 4-Me, etc.; R 1 = Me, iso-Pr, benzyl, etc.] and external aromatic nucleophiles [such as 1,3,5-trimethoxybenzene, 1-naphthol, 1H-indole, etc.] for the construction of spiroisoindolinone indenes II [R 2 = H, 7-Me, 6-Cl, 5-Me, etc.], e.g., III is described. The reaction proceeds rapidly with a broad range of substrates to generate spiroindenes II, e.g., III chemoselectively and regioselectively in moderate to high yields. Key to the success of this transformation is an intercepted Meyer-Schuster rearrangement/intramol. Friedel-Crafts alkylation relay that offers a modular approach in the synthesis of target compds II, e.g., III.
Journal of Organic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H17Br, SDS of cas: 91-16-7.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem