Das, Amrita published the artcileRh(II)-Catalyzed C-H Alkylation of Benzylamines with Unactivated Alkenes: The Influence of Acid on Linear and Branch Selectivity, HPLC of Formula: 6850-57-3, the publication is Organic Letters (2021), 23(11), 4273-4278, database is CAplus and MEDLINE.
The Rh-catalyzed C-H alkylation of benzylamine derivatives 2RC6H4CH2NHC(O)R1 (R = Me, methoxy, trifluoromethyl; R1 = pyridin-2-yl) and I (X = H) with unactivated 1-alkenes R2HC=CH2 (R2 = pentyl, cyclohexylmethyl, 4-(acetyloxy)butyl, etc.) that proceeds via a picolinamide directing group is reported. The crucial role of an acid additive in this transformation is confirmed. Aromatic acids showed high linear selective products e.g., N-(2-heptyl-6-methylbenzyl)picolinamide, and aliphatic acids provided branched alkylation products e.g., N-(2-(hexan-2-yl)-6-methylbenzyl)picolinamide as the major product. The reaction has a broad scope for benzylamines and alkenes. Deuterium labeling experiments suggest that a Rh-carbene intermediate is involved in the case of linear product formation. A different reaction pathway, however, appears to be involved in the case of branched alkylation products, and this pathway also appeared to be a minor pathway in linear-selective reactions.
Organic Letters published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, HPLC of Formula: 6850-57-3.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem