Monopoli, Antonio published the artcileA new expeditious synthesis of the core scaffold of salvianolic acid F trough a one-pot sequential Heck coupling catalyzed by palladium nanoparticles in ionic liquids, SDS of cas: 91-16-7, the publication is Journal of Organometallic Chemistry (2022), 122193, database is CAplus.
A new expeditious synthesis of tetra-Me salvianolic acid F (I) is presented. Starting from the naturally occurring veratrole, the target mol. is easily obtained in a one-pot mode via a sequential double Heck coupling catalyzed by palladium nanoparticles dispersed in ionic liquids The present method involves the chemoselective displacement of two different halogen atoms present on the veratrole ring and limits the need for tedious exptl. procedures. A 66% of overall yield can be achieved, that represents, as far as we know, one of the best results present in the literature, until now. This protocol can also open the way for the synthesis of unnatural salvianolic-like compounds with potential bioactivity.
Journal of Organometallic Chemistry published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 91-16-7.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem