Organic Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Synthetic Route of 99438-28-5.
Hanessian, Stephen published the artcileAlternative and Expedient Asymmetric Syntheses of L-(+)-Noviose, Synthetic Route of 99438-28-5, the publication is Organic Letters (2008), 10(2), 261-264, database is CAplus and MEDLINE.
L-(+)-Noviose I, the sugar component of the antibiotic novobiocin, was synthesized from either 2,2-dimethyl-1,3-cyclopentadione or benzyl glyoxylate relying on stoichiometric and asym. processes by two independent methods, comprising six and nine steps, in 27 and 20% overall yields, resp. An unsaturated lactone II was prepared via stereoselective boron-catalyzed reduction, scandium-catalyzed Baeyer-Villiger oxidation and Saegusa oxidation from 2,2-dimethyl-1,3-cyclopentadione. II could also be prepared via stereoselective Brown allylation, ruthenium-catalyzed isomerization and ring-closing metathesis, and allylic oxidation from benzyl glyoxylate. II was then transformed to I via stereoselective reduction and dihydroxylation.
Organic Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Synthetic Route of 99438-28-5.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem