Horton, Martin N. published the artcileSynthesis of [D5-ethyl]-tamoxifen; a mechanistic probe of tamoxifen induced hepatic DNA adduct formation, Related Products of ethers-buliding-blocks, the main research area is tamoxifen deuterated.
Tamoxifen which incorporates a fully deuterated Et group, [D5-ethyl]-tamoxifen, has been synthesized in order to probe the mechanism of tamoxifen induced hepatic DNA adduct formation. The pentadeuteroethyl group was introduced into the tamoxifen structure by treatment of the ketone precursor 1-[4-(2-chloroethoxy)phenyl]-2-phenylethanone, as its sodium enolate, with [D5]-iodoethane.
Journal of Labelled Compounds and Radiopharmaceuticals published new progress about tamoxifen deuterated. 622-86-6 belongs to class ethers-buliding-blocks, name is (2-Chloroethoxy)benzene, and the molecular formula is C8H9ClO, Related Products of ethers-buliding-blocks.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem