Bolton, P. D. published the artcileHydrolysis of amides. III. Dilute acid hydrolysis of amides of the type RCH2CONH2, COA of Formula: C3H7NO2, the main research area is amides acid hydrolysis kinetics; acid hydrolysis kinetics amides; hydrolysis acid kinetics amides.
Rate constants over a range of temperature, enthalpies of activation, and entropies of activation are reported for the dilute acid hydrolysis of n-valeramide, isovaleramide, 3,3-dimethylbutanamide, phenylacetamide, cyclohexylacetamide, methoxyacetamide, bromoacetamide, and chloroacetamide. The rate constants of the first six amides together with those of two other alkyl-substituted acetamides determined earlier are almost perfectly correlated by the Taft linear steric energy relation. The enthalpies of activation, also, show a linear dependence on the steric parameter, Es. The results obtained for the halo amides indicate that the acid hydrolysis of amides may show a slight sensitivity to polar effects.
Australian Journal of Chemistry published new progress about Entropy. 16332-06-2 belongs to class ethers-buliding-blocks, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, COA of Formula: C3H7NO2.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem