Fujihira, Yamato published the artcilePentafluoroethylation of Carbonyl Compounds by HFC-125 via the Encapsulation of the K Cation with Glymes, Application of 2,5,8,11,14-Pentaoxapentadecane, the main research area is pentafluoroethylation carbonyl compound HFC 125 encapsulation potassium cation glyme.
A simple protocol to overcome the explosive pentafluoroethylation of carbonyl compounds by HFC-125 is described. The use of potassium (K) bases with triglyme or tetraglyme as a solvent safely yields the pentafluoroethylation products in good to high yields. The exptl. results suggest that an encapsulation of the K cation by glymes as K(glyme)2 inhibits the contact between the K cation and the reactive anionic pentafluoroethyl counterion, preventing their transformation into KF and explosive tetrafluoroethylene (TFE). The generation of sterically demanding [K(G3)2]+ and [K(G4)2]+ is an effective way as an unstable pentafluoroethyl anion reservoir.
Journal of Organic Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 143-24-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11,14-Pentaoxapentadecane, and the molecular formula is C10H22O5, Application of 2,5,8,11,14-Pentaoxapentadecane.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem