Sapotta, Meike published the artcileA Water-Soluble Perylene Bisimide Cyclophane as a Molecular Probe for the Recognition of Aromatic Alkaloids, Quality Control of 23783-42-8, the main research area is perylene bisimide cyclophane mol probe aromatic alkaloid; alkaloids; cyclophanes; fluorescence probes; host-guest systems; perylene bisimides.
Herein, we report a water-soluble macrocyclic host based on perylene bisimide (PBI) chromophores that recognizes natural aromatic alkaloids in aqueous media by intercalating them into its hydrophobic cavity. The host-guest binding properties of our newly designed receptor with several alkaloids were studied by UV/Vis and fluorescence titration experiments as the optical properties of the chromophoric host change significantly upon complexation of guests. Structural information on the host-guest complexes was obtained by 1D and 2D NMR spectroscopy and mol. modeling. Our studies reveal a structure-binding property relationship for a series of structurally diverse aromatic alkaloids with the new receptor and higher binding affinity for the class of harmala alkaloids. To our knowledge, this is the first example of a chromophoric macrocyclic host employed as a mol. probe for the recognition of aromatic alkaloids.
Angewandte Chemie, International Edition published new progress about Alkaloids Role: ANT (Analyte), ANST (Analytical Study) (aromatic). 23783-42-8 belongs to class ethers-buliding-blocks, name is 2,5,8,11-Tetraoxatridecan-13-ol, and the molecular formula is C9H20O5, Quality Control of 23783-42-8.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem